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ALDH6A1 Rabbit pAb

Anti-ALDH6A1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216974

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216974
Product Name:   Anti-ALDH6A1 Rabbit Polyclonal Antibody
Synonyms:   MMSDH; MMSADHA
UNIPROT ID:   Q02252 (Gene Accession – BC004909 )
Background:    This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Immunogen:    Fusion protein of human ALDH6A1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216974(ALDH6A1 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216974(Anti-ALDH6A1 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 216974(Anti-ALDH6A1 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D221570(Anti-ALDH6A1 Antibody) at dilution 1/45.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: Rat kidney tissue, human fetal kidney tissue, Jurkat cells, K562 cells;
Primary antibody: 216974(ALDH6A1 Antibody) at dilution 1/450;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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