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ALDOA Rabbit pAb

Anti-ALDOA Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216321

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216321
Product Name:   Anti-ALDOA Rabbit Polyclonal Antibody
Synonyms:   ALDA; GSD12; HEL-S-87p
UNIPROT ID:   P04075 (Gene Accession – BC004333 )
Background:    This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
Immunogen:    Fusion protein of human ALDOA
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216321(ALDOA Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216321(Anti-ALDOA Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 216321(Anti-ALDOA Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D220203(Anti-ALDOA Antibody) at dilution 1/55.

Gel: 8%SDS-PAGE, Lysate:40 μg;
Lane: Mouse brain tissue lysates;
Primary antibody: 216321(ALDOA Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 seconds
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