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AMBRA1 Rabbit pAb

Anti-AMBRA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216994

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216994
Product Name:   Anti-AMBRA1 Rabbit Polyclonal Antibody
Synonyms:   DCAF3; WDR94
UNIPROT ID:   Q9C0C7 (Gene Accession – BC045609 )
Background:    Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.
Immunogen:    Fusion protein of human AMBRA1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lymphoma tissue using 216994(AMBRA1 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lymphoma tissue is first treated with the fusion protein and then with 216994(Anti-AMBRA1 Antibody) at dilution 1/25.
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