Email: info@neweastbio.com   |  Call: 6109452007

AMPD1 Rabbit pAb

Anti-AMPD1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220291

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220291
Product Name:   Anti-AMPD1 Rabbit Polyclonal Antibody
Synonyms:   MAD; MADA
UNIPROT ID:   P23109 (Gene Accession – NP_000027 )
Background:    Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Immunogen:    Synthetic peptide of human AMPD1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 500-2000;ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220291(AMPD1 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220291(Anti-AMPD1 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220291(Anti-AMPD1 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D261272(Anti-AMPD1 Antibody) at dilution 1/70.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human fetal muscle tissue;
Primary antibody: 220291(AMPD1 Antibody) at dilution 1/1600;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 3 seconds
          Publications