NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261839 |
Product Name: Anti-AMPK gamma 1 Rabbit Monoclonal Antibody |
Synonyms: AMPKG |
UNIPROT ID: P54619 |
Background: AMPK is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis.Accumulating evidence indicates that AMPK not only regulates the metabolism of fatty acids and glycogen, but also modulates protein synthesis and cell growth through EF2 and TSC2/mTOR pathways, as well as blood flow via eNOS/nNOS. |
Immunogen: A synthetic peptide of human AMPK gamma 1 |
Applications: WB,IP |
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R08-7D5 |
MW: Calculated MW: 38 kDa; Observed MW: 38 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human,Rat |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Cardiovascular |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of AMPK gamma 1 in CHO-K1, C6, Jurkat lysates using AMPK gamma 1 antibody. |