Email: info@neweastbio.com   |  Call: 6109452007

AMZ2 Rabbit pAb

Anti-AMZ2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217030

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217030
Product Name:   Anti-AMZ2 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q86W34 (Gene Accession – BC050709 )
Background:    AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.
Immunogen:    Fusion protein of human AMZ2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 217030(AMZ2 Antibody) at a dilution of 1/60(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the fusion protein and then with 217030(Anti-AMZ2 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 217030(Anti-AMZ2 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D221674(Anti-AMZ2 Antibody) at dilution 1/60.
          Publications