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ANGPTL4 Rabbit pAb

Anti-ANGPTL4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216326

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216326
Product Name:   Anti-ANGPTL4 Rabbit Polyclonal Antibody
Synonyms:   NL2, ARP4, FIAF, PGAR, HFARP, pp1158, ANGPTL2
UNIPROT ID:   Q9BY76 (Gene Accession – BC023647 )
Background:    This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
Immunogen:    Fusion protein of human ANGPTL4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Metabolism, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human esophagus cancer tissue using 216326(ANGPTL4 Antibody) at a dilution of 1/25(Cytoplasm, Cell membrane).
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