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ANKMY2 Rabbit pAb

Anti-ANKMY2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217005

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217005
Product Name:   Anti-ANKMY2 Rabbit Polyclonal Antibody
Synonyms:   ZMYND20
UNIPROT ID:   Q8IV38 (Gene Accession – BC035353 )
Background:    ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Immunogen:    Fusion protein of human ANKMY2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217005(ANKMY2 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217005(Anti-ANKMY2 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 217005(Anti-ANKMY2 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D221627(Anti-ANKMY2 Antibody) at dilution 1/30.
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