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AP2M1 Rabbit pAb

Anti-AP2M1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217010

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217010
Product Name:   Anti-AP2M1 Rabbit Polyclonal Antibody
Synonyms:   mu2; AP50; CLAPM1
UNIPROT ID:   Q96CW1 (Gene Accession – BC013796 )
Background:    This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human AP2M1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 217010(AP2M1 Antibody) at a dilution of 1/15(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 217010(Anti-AP2M1 Antibody) at dilution 1/15.
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