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APBA2 Rabbit pAb

Anti-APBA2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220296

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220296
Product Name:   Anti-APBA2 Rabbit Polyclonal Antibody
Synonyms:   X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
UNIPROT ID:   Q99767 (Gene Accession – NP_001123886 )
Background:    The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer’s disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer’s disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human APBA2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220296(APBA2 Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220296(Anti-APBA2 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220296(Anti-APBA2 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D261289(Anti-APBA2 Antibody) at dilution 1/80.
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