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APE1 Rabbit mAb

Anti-APE1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261855

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261855
Product Name:   Anti-APE1 Rabbit Monoclonal Antibody
Synonyms:   APEX1; APE; APE1; APEX; APX; HAP1; REF1; DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1
UNIPROT ID:   P27695
Background:    Ape1 initiates the repair of abasic sites and is essential for the base excision repair (BER) pathway. Repair activities of Ape1 are stimulated by interaction with XRCC1, another essential protein in BER. Ape1 functions as a redox factor that maintains transcription factors in an active, reduced state but can also function in a redox-independent manner as a transcriptional cofactor to control different cellular fates such as apoptosis, proliferation and differentiation.
Immunogen:    Recombinant protein of human APE1
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R01-6G2
MW:    Calculated MW: 36 kDa; Observed MW: 36 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of APE1(green) in Hela using APE1 antibody,and DAPI(blue)

Western blot analysis of APE1 in K562, C6, 3T3, Hela lysates using APE1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using APE1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications