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APLP1 Rabbit pAb

Anti-APLP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216249

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216249
Product Name:   Anti-APLP1 Rabbit Polyclonal Antibody
Synonyms:   APLP
UNIPROT ID:   P51693 (Gene Accession – BC012889 )
Background:    This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Immunogen:    Fusion protein of human APLP1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: Oct-50;WB: 500-2000;ELISA: 500-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using 216249(APLP1 Antibody) at a dilution of 1/10(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 216249(Anti-APLP1 Antibody) at a dilution of 1/10.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human fetal brain tissue;
Primary antibody: 216249(APLP1 Antibody) at dilution 1/650;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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