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ARFIP2 Rabbit pAb

Anti-ARFIP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219555

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219555
Product Name:   Anti-ARFIP2 Rabbit Polyclonal Antibody
Synonyms:   POR1
UNIPROT ID:   P53365 (Gene Accession – BC000392 )
Background:    Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658).
Immunogen:    Fusion protein of human ARFIP2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219555(ARFIP2 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 219555(Anti-ARFIP2 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219555(Anti-ARFIP2 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D227715(Anti-ARFIP2 Antibody) at dilution 1/70.
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