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Argonaute 2 Rabbit mAb

Anti-Argonaute 2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261867

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261867
Product Name:   Anti-Argonaute 2 Rabbit Monoclonal Antibody
Synonyms:   Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD
UNIPROT ID:   Q9UKV8
Background:    Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3′-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
Immunogen:    A synthetic peptide of human Argonaute-2
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-5H0
MW:    Calculated MW: 97 kDa; Observed MW: 97 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Argonaute2 in K562, MCF-7, Hela lysates using Argonaute2 antibody.

Immunocytochemistry analysis of Argonaute 2 (green) in HCT116 using Argonaute 2 antibody,and DAPI(blue).
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