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ASCL1 Rabbit pAb

Anti-ASCL1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219663

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219663
Product Name:   Anti-ASCL1 Rabbit Polyclonal Antibody
Synonyms:   ASH1; HASH1; MASH1; bHLHa46
UNIPROT ID:   P50553 (Gene Accession – NP_004307 )
Background:    This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5′-CANNTG-3′). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Immunogen:    Synthetic peptide of human ASCL1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 3000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 219663(ASCL1 Antibody) at a dilution of 1/30(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 219663(Anti-ASCL1 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 219663(Anti-ASCL1 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D260108(Anti-ASCL1 Antibody) at dilution 1/30.
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