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ASIC3 Rabbit pAb

Anti-ASIC3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220356

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220356
Product Name:   Anti-ASIC3 Rabbit Polyclonal Antibody
Synonyms:   ACCN3; TNaC1; DRASIC; SLNAC1
UNIPROT ID:   Q9UHC3 (Gene Accession – NP_004760 )
Background:    This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
Immunogen:    Synthetic peptide of human ASIC3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 220356(ASIC3 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 220356(Anti-ASIC3 Antibody) at dilution 1/40.
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