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ATG4D Rabbit pAb

Anti-ATG4D Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217066

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217066
Product Name:   Anti-ATG4D Rabbit Polyclonal Antibody
Synonyms:   APG4D; AUTL4; APG4-D
UNIPROT ID:   Q86TL0 (Gene Accession – BC007639 )
Background:    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes.
Immunogen:    Fusion protein of human ATG4D
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cell Biology, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217066(ATG4D Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217066(Anti-ATG4D Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 217066(Anti-ATG4D Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D221732(Anti-ATG4D Antibody) at dilution 1/40.
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