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ATP6V0D1 Rabbit mAb

Anti-ATP6V0D1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261895

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261895
Product Name:   Anti-ATP6V0D1 Rabbit Monoclonal Antibody
Synonyms:   P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD
UNIPROT ID:   P61421
Background:    Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis . May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium . In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).
Immunogen:    Recombinant protein of human ATP6V0D1
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-1A5
MW:    Calculated MW: 40 kDa; Observed MW: 40 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of ATP6V0D1(green) in Hela using ATP6V0D1 antibody,and DAPI(blue)

Western blot analysis of ATP6V0D1 in K562, rat Brain, C6, 3T3, Hela lysates using ATP6V0D1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using ATP6V0D1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications