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BACE1 Rabbit mAb

Anti-BACE1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261904

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261904
Product Name:   Anti-BACE1 Rabbit Monoclonal Antibody
Synonyms:   ASP2; Bace; C76936
UNIPROT ID:   P56818
Background:    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.
Immunogen:    Recombinant protein of mouse BACE1
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-9C8
MW:    Calculated MW: 56 kDa; Observed MW: 70 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    NeuroscienceyyyyyAlzheimer’s disease
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of BACE1 in rat Brain lysates using BACE1 antibody.
          Publications