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Bad Rabbit mAb

Anti-Bad Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261905

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261905
Product Name:   Anti-Bad Rabbit Monoclonal Antibody
Synonyms:   BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter
UNIPROT ID:   Q92934
Background:    Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Immunogen:    A synthetic peptide of human Bad
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-1B6
MW:    Calculated MW: 18 kDa; Observed MW: 23 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    apoptosis – Bcl-2 family
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Bad antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Bad in rat Brain, C6, 3T3, Hela lysates using Bad antibody.

Immunocytochemistry analysis of Bad(green) in Hela using Bad antibody,and DAPI(blue)
          Publications