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Bax Rabbit mAb

Anti-Bax Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261915

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261915
Product Name:   Anti-Bax Rabbit Monoclonal Antibody
Synonyms:   Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
UNIPROT ID:   Q07812
Background:    Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane’s permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
Immunogen:    A synthetic peptide of human Bax
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-5F2
MW:    Calculated MW: 21 kDa; Observed MW: 21 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Bax in C6, 3T3, Hela lysates using Bax antibody.
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