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BCL3 Rabbit pAb

Anti-BCL3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220098

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220098
Product Name:   Anti-BCL3 Rabbit Polyclonal Antibody
Synonyms:   BCL4; D19S37
UNIPROT ID:   P20749 (Gene Accession – NP_005169 )
Background:    This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
Immunogen:    Synthetic peptide of human BCL3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 220098(BCL3 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 220098(Anti-BCL3 Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220098(Anti-BCL3 Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D260954(Anti-BCL3 Antibody) at dilution 1/15.
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