Email: info@neweastbio.com   |  Call: 6109452007

BIRC7 Rabbit pAb

Anti-BIRC7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221314

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221314
Product Name:   Anti-BIRC7 Rabbit Polyclonal Antibody
Synonyms:   KIAP; LIVIN; MLIAP; RNF50; ML-IAP
UNIPROT ID:   Q96CA5 (Gene Accession – NP_071444 )
Background:    This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants
Immunogen:    Synthetic peptide of human BIRC7
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 221314(BIRC7 Antibody) at a dilution of 1/30(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 221314(Anti-BIRC7 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 221314(Anti-BIRC7 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D262850(Anti-BIRC7 Antibody) at dilution 1/30.
          Publications