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BMPR2 Rabbit pAb

Anti-BMPR2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216881

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216881
Product Name:   Anti-BMPR2 Rabbit Polyclonal Antibody
Synonyms:   BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II
UNIPROT ID:   Q13873 (Gene Accession – BC052985 )
Background:    This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
Immunogen:    Fusion protein of human BMPR2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 216881(BMPR2 Antibody) at a dilution of 1/35(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 216881(Anti-BMPR2 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 216881(Anti-BMPR2 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D221406(Anti-BMPR2 Antibody) at dilution 1/35.
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