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BTNL2 Rabbit pAb

Anti-BTNL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218142

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218142
Product Name:   Anti-BTNL2 Rabbit Polyclonal Antibody
Synonyms:   SS2; BTN7; BTL-II; HSBLMHC1
UNIPROT ID:   Q9UIR0 (Gene Accession – BC127642 )
Background:    This gene encodes a major histocompatibility comple,x class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.
Immunogen:    Fusion protein of human BTNL2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 200-400;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218142(BTNL2 Antibody) at a dilution of 1/220(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218142(Anti-BTNL2 Antibody) at dilution 1/220.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 218142(Anti-BTNL2 Antibody) at a dilution of 1/220.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D223807(Anti-BTNL2 Antibody) at dilution 1/220.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse kidney tissue lysate;
Primary antibody: 218142(BTNL2 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 40 seconds
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