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BUB1 Rabbit pAb

Anti-BUB1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217222

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217222
Product Name:   Anti-BUB1 Rabbit Polyclonal Antibody
Synonyms:   BUB1A; BUB1L; hBUB1
UNIPROT ID:   O43683 (Gene Accession – BC028201 )
Background:    This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human BUB1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 217222(BUB1 Antibody) at a dilution of 1/60(Nucleus and Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 217222(Anti-BUB1 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 217222(Anti-BUB1 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D222004(Anti-BUB1 Antibody) at dilution 1/60.
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