Email: info@neweastbio.com   |  Call: 6109452007

BUBR1 Rabbit mAb

Anti-BUBR1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263242

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263242
Product Name:   Anti-BUBR1 Rabbit Monoclonal Antibody
Synonyms:   BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1
UNIPROT ID:   O60566
Background:    Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.
Immunogen:    A synthetic peptide of human BubR1
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R01-4C1
MW:    Calculated MW: 120 kDa; Observed MW: 120 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of BubR1 (green) in hela using BubR1 antibody,and DAPI(blue)

Western blot analysis of BubR1 in Hela, A549, MCF-7, U251 lysates using BUBR1 antibody.
          Publications