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C3/C3b Rabbit pAb

Anti-C3/C3b Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221654

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221654
Product Name:   Anti-C3/C3b Rabbit Polyclonal Antibody
Synonyms:   ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
UNIPROT ID:   P01024 (Gene Accession – NP_000055 )
Background:    Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Immunogen:    Synthetic peptide of human C3/C3b
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221654(C3/C3b Antibody) at a dilution of 1/35(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221654(Anti-C3/C3b Antibody) at dilution 1/35.
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