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C9orf116 Rabbit pAb

Anti-C9orf116 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218788

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218788
Product Name:   Anti-C9orf116 Rabbit Polyclonal Antibody
Synonyms:   PIERCE1; RbEST47
UNIPROT ID:   Q5BN46 (Gene Accession – BC021261 )
Background:    C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.
Immunogen:    Fusion protein of human C9orf116
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 218788(C9orf116 Antibody) at a dilution of 1/55(Cytoplasm).
          Publications