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CA5B Rabbit pAb

Anti-CA5B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221657

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221657
Product Name:   Anti-CA5B Rabbit Polyclonal Antibody
Synonyms:   CA-VB
UNIPROT ID:   Q9Y2D0 (Gene Accession – NP_009151 )
Background:    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
Immunogen:    Synthetic peptide of human CA5B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221657(CA5B Antibody) at a dilution of 1/85(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221657(Anti-CA5B Antibody) at dilution 1/85.
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