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CABIN1 Rabbit pAb

Anti-CABIN1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215426

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215426
Product Name:   Anti-CABIN1 Rabbit Polyclonal Antibody
Synonyms:   CAIN; PPP3IN; KB-318B8.7
UNIPROT ID:   Q9Y6J0 (Gene Accession – NP_036427 )
Background:    Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.
Immunogen:    Synthetic peptide of human CABIN1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 215426(CABIN1 Antibody) at a dilution of 1/50(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 215426(Anti-CABIN1 Antibody) at dilution 1/50.
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