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Cadherin 5 Rabbit mAb

Anti-Cadherin 5 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263064

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263064
Product Name:   Anti-Cadherin 5 Rabbit Monoclonal Antibody
Synonyms:   7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225
UNIPROT ID:   P55284
Background:    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
Immunogen:    Recombinant protein of mouse VE Cadherin
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-3F8
MW:    Calculated MW: 88 kDa; Observed MW: 90-140 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of VE Cadherin in mouse lung lysates using Cadherin 5 antibody.
          Publications