Email: info@neweastbio.com   |  Call: 6109452007

Cadherin 5 Rabbit pAb

Anti-Cadherin 5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225099

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225099
Product Name:   Anti-Cadherin 5 Rabbit pAb
Synonyms:   CDH5; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD antigen CD144
UNIPROT ID:   P33151
Background:    This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Immunogen:    The antiserum was produced against synthesized peptide derived from human CDH5. AA range:697-746
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 88 kDa; Observed MW: 120 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Cadherin 5 in A549 lysates using Cadherin 5 antibody.

Western blot analysis of Cadherin 5 in Jurkat lysates using Cadherin 5 antibody.
          Publications