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CAPN9 Rabbit pAb

Anti-CAPN9 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221671

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221671
Product Name:   Anti-CAPN9 Rabbit Polyclonal Antibody
Synonyms:   GC36; nCL-4
UNIPROT ID:   O14815 (Gene Accession – NP_006606 )
Background:    Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human CAPN9
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221671(CAPN9 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221671(Anti-CAPN9 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 221671(Anti-CAPN9 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D263371(Anti-CAPN9 Antibody) at dilution 1/45.
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