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CASC3 Rabbit pAb

Anti-CASC3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217244

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217244
Product Name:   Anti-CASC3 Rabbit Polyclonal Antibody
Synonyms:   BTZ; MLN51
UNIPROT ID:   O15234 (Gene Accession – BC050526 )
Background:    The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.
Immunogen:    Fusion protein of human CASC3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 217244(CASC3 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 217244(Anti-CASC3 Antibody) at dilution 1/20.
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