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CASK Rabbit pAb

Anti-CASK Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218430

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218430
Product Name:   Anti-CASK Rabbit Polyclonal Antibody
Synonyms:   CMG; FGS4; LIN2; TNRC8; CAGH39; CAMGUK; MICPCH; MRXSNA
UNIPROT ID:   O14936 (Gene Accession – BC117311 )
Background:    This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human CASK
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 40-200;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218430(CASK Antibody) at a dilution of 1/45(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218430(Anti-CASK Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 218430(Anti-CASK Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D224416(Anti-CASK Antibody) at dilution 1/45.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: Human cerebrum tissue lysate;
Primary antibody: 218430(CASK Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes
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