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Caspase 11 Rabbit mAb

Anti-Caspase 11 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261961

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261961
Product Name:   Anti-Caspase 11 Rabbit Monoclonal Antibody
Synonyms:   Caspl; ich-3; CASP-4; Casp11; CASP-11
UNIPROT ID:   P70343
Background:    Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators.
Immunogen:    Recombinant protein of mouse Caspase-11
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-7H9
MW:    Calculated MW: 43 kDa; Observed MW: 43,38,25 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    apoptosis – Caspase family
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Caspase11 in C6, 3T3, Hela lysates using Caspase 11 antibody.
          Publications