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CBFA2T3 Rabbit pAb

Anti-CBFA2T3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221682

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221682
Product Name:   Anti-CBFA2T3 Rabbit Polyclonal Antibody
Synonyms:   ETO2; MTG16; MTGR2; ZMYND4; RUNX1T3
UNIPROT ID:   O75081 (Gene Accession – NP_005178 )
Background:    This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5′-region of the runt-related transcription factor 1 gene fused to the 3′-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Immunogen:    Synthetic peptide of human CBFA2T3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221682(CBFA2T3 Antibody) at a dilution of 1/45(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221682(Anti-CBFA2T3 Antibody) at dilution 1/45.
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