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CBR1 Rabbit pAb

Anti-CBR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217157

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217157
Product Name:   Anti-CBR1 Rabbit Polyclonal Antibody
Synonyms:   CBR; hCBR1; SDR21C1
UNIPROT ID:   P16152 (Gene Accession – BC002511 )
Background:    Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
Immunogen:    Fusion protein of human CBR1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 217157(CBR1 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 217157(Anti-CBR1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 217157(Anti-CBR1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with fusion protein and then with D221894(Anti-CBR1 Antibody) at dilution 1/40.

Gel: 15%SDS-PAGE, Lysate: 40 μg;
Lane 1-6: Mouse liver tissue, human fetal lung tissue, hela cells, mouse kidney tissue, human brain malignant glioma tissue, K562 cells;
Primary antibody: 217157(CBR1 Antibody) at dilution 1/1000;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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