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CBX1 Rabbit pAb

Anti-CBX1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219683

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219683
Product Name:   Anti-CBX1 Rabbit Polyclonal Antibody
Synonyms:   CBX; M31; MOD1; p25beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta
UNIPROT ID:   P83916 (Gene Accession – NP_001120700 )
Background:    This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.
Immunogen:    Synthetic peptide of human CBX1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 219683(CBX1 Antibody) at a dilution of 1/30(Nucleus ).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 219683(Anti-CBX1 Antibody) at dilution 1/30.
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