Email: info@neweastbio.com   |  Call: 6109452007

CCDC88A Rabbit pAb

Anti-CCDC88A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S214158

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S214158
Product Name:   Anti-CCDC88A Rabbit Polyclonal Antibody
Synonyms:   APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
UNIPROT ID:   Q3V6T2 (Gene Accession – NP_001129069 )
Background:    This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen:    Synthetic peptide of human CCDC88A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 214158(CCDC88A Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 214158(Anti-CCDC88A Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 214158(Anti-CCDC88A Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with synthetic peptide and then with D161438(Anti-CCDC88A Antibody) at dilution 1/50.
          Publications