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CCL2 Rabbit pAb

Anti-CCL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219686

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219686
Product Name:   Anti-CCL2 Rabbit Polyclonal Antibody
Synonyms:   HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30
UNIPROT ID:   P13500 (Gene Accession – NP_002973 )
Background:    This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Immunogen:    Synthetic peptide of human CCL2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cardiovascular, Metabolism, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 219686(CCL2 Antibody) at a dilution of 1/50(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 219686(Anti-CCL2 Antibody) at dilution 1/50.
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