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CD163 Rabbit pAb

Anti-CD163 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220105

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220105
Product Name:   Anti-CD163 Rabbit Polyclonal Antibody
Synonyms:   M130; MM130
UNIPROT ID:   Q86VB7 (Gene Accession – NP_004235 )
Background:    The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen:    Synthetic peptide of human CD163
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cardiovascular, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 220105(CD163 Antibody) at a dilution of 1/30(secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 220105(Anti-CD163 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220105(Anti-CD163 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D260965(Anti-CD163 Antibody) at dilution 1/30.
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