Email: info@neweastbio.com   |  Call: 6109452007

CD44 Rabbit pAb

Anti-CD44 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220318

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220318
Product Name:   Anti-CD44 Rabbit Polyclonal Antibody
Synonyms:   IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III
UNIPROT ID:   P16070 (Gene Accession – NP_000601 )
Background:    The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Immunogen:    Synthetic peptide of human CD44
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer using 220318(CD44 Antibody) at a dilution of 1/45(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer is first treated with the synthetic peptide and then with 220318(Anti-CD44 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer using 220318(Anti-CD44 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer is first treated with synthetic peptide and then with D261338(Anti-CD44 Antibody) at dilution 1/45.
          Publications