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CD45 (8C1) Mouse mAb

Anti-CD45 (8C1) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261211

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261211
Product Name:   Anti-CD45 (8C1) Mouse Monoclonal Antibody
Synonyms:   GP180; L CA; CD45 antigen
UNIPROT ID:   P06800
Background:    Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
Immunogen:    Synthetic Peptide of CD45
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    8C1-9B8-2H1
MW:    Calculated MW: 145 kDa; Observed MW: 145 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    NeuroscienceyyyyyMicroglia
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using CD45 (8C1) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only.

Immunofluorescence analysis of CD45 (8C1) in Human livercancer tissue using CD45 (8C1) antibody(red),and DAPI (blue).

Western blot analysis of CD45 (8C1) in Jurkat lysates using CD45 (8C1) antibody.
          Publications