Email: info@neweastbio.com   |  Call: 6109452007

CD8A Rabbit pAb

Anti-CD8A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221698

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221698
Product Name:   Anti-CD8A Rabbit Polyclonal Antibody
Synonyms:   CD8; MAL; p32; Leu2
UNIPROT ID:   P01732 (Gene Accession – NP_001759 )
Background:    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human CD8A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 221698(CD8A Antibody) at a dilution of 1/100(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the synthetic peptide and then with 221698(Anti-CD8A Antibody) at dilution 1/100.
          Publications