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CDK5 (2E8) Mouse mAb

Anti-CDK5 (2E8) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261047

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261047
Product Name:   Anti-CDK5 (2E8) Mouse Monoclonal Antibody
Synonyms:   Cdk 5; Cdk5; CDK5_HUMAN; Cell division protein kinase 5; Crk6; Cyclin dependent kinase 5; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit.
UNIPROT ID:   Q00535
Background:    Activated by cyclins but by p35 (CDK5R1) and p39. An important regulator of neuronal positioning during brain development. May also play a role in synaptogenesis and neurotransmission. Substrates include TAU, MAP2, NF-H and -M, Nudel, PDE6, beta-catenin, amphyphysin, dynamin I, synapsin 1, Munc-18, and NMDA receptor 2A. Plays a role in myogenesis, haematopoietic cell differentiation, spermatogenesis, insulin secretion, and lens differentiation.
Immunogen:    Purified recombinant human CDK5(N-terminus) protein fragments expressed in E.coli.
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    2E8-F9-B7-C11
MW:    Calculated MW: 33 kDa; Observed MW: 36 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat,Monkey
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    NeuroscienceyyyyyAlzheimer’s disease
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of CDK5 in HeLa cells using CDK5 antibody.

Western blot analysis of CDK5(Nterminus) in 3T3, Hela, PC-12, COS7, Jurkat and K562 lysates using Cdk5 antibody.
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