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CDK7 Rabbit pAb

Anti-CDK7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216413

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216413
Product Name:   Anti-CDK7 Rabbit Polyclonal Antibody
Synonyms:   CAK1, HCAK, MO15, STK1, CDKN7, p39MO15
UNIPROT ID:   P50613 (Gene Accession – BC000834 )
Background:    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Immunogen:    Fusion protein of human CDK7
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 15-50;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216413(CDK7 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216413(Anti-CDK7 Antibody) at dilution 1/30.

Gel: 10%SDS-PAGE, Lysate: 60 μg;
Lane: A549 cells;
Primary antibody: 216413(CDK7 Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes
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