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CDKN1C Rabbit pAb

Anti-CDKN1C Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213422

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213422
Product Name:   Anti-CDKN1C Rabbit Polyclonal Antibody
Synonyms:   BWS; WBS; p57; BWCR; KIP2; p57Kip2
UNIPROT ID:   P49918 (Gene Accession – NP_000067 )
Background:    This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human CDKN1C
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 213422(CDKN1C Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 213422(Anti-CDKN1C Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 213422(Anti-CDKN1C Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D160160(Anti-CDKN1C Antibody) at dilution 1/50.
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