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CFB Rabbit pAb

Anti-CFB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218144

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218144
Product Name:   Anti-CFB Rabbit Polyclonal Antibody
Synonyms:   BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14
UNIPROT ID:   P00751 (Gene Accession – BC004143 )
Background:    This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5′ end of the gene for complement component 2.
Immunogen:    Fusion protein of human CFB
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 218144(CFB Antibody) at a dilution of 1/70(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 218144(Anti-CFB Antibody) at a dilution of 1/70.
          Publications